Abstract | UNLABELLED: METHOD AND MATERIALS: A split mouth design was used so that each patient received all treatments simultaneously. Randomly selected quadrants were treated with applications of 25% metronidazole gel, subgingival scaling, or a combination of scaling and gel application. The remaining quadrant in each patient was left untreated as a control. RESULTS: All three treatments were effective in significantly reducing bleeding on probing over the 14 weeks observation period. No statistically significant differences were found between scaling alone and combined treatment. Scaling and combined treatment were better than metronidazole. Metronidazole produced transient effects, best noted during the first 4 weeks after treatment. No additive effect of metronidazole was noted in the combined treatment. At week 14, only combined treatment sites and scaled showed statistically greater probing depths reduction than control sites. CONCLUSION:
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Authors | S Mârţu, C Mocanu, C G Popovici |
Journal | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
(Rev Med Chir Soc Med Nat Iasi)
2000 Apr-Jun
Vol. 104
Issue 2
Pg. 125-30
ISSN: 0048-7848 [Print] Romania |
Vernacular Title | Studiul comparativ al efectului metronidazolului în aplicaţii subgingivale în tratamentul parodontitei adultului. |
PMID | 12089976
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Infective Agents
- Gels
- Metronidazole
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Topics |
- Adult
- Anti-Infective Agents
(therapeutic use)
- Combined Modality Therapy
- Dental Scaling
(methods)
- Gels
- Humans
- Metronidazole
(therapeutic use)
- Middle Aged
- Periodontal Index
- Periodontitis
(therapy)
- Single-Blind Method
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