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Plasma catecholamine metabolites in antidepressant-exacerbated mania and psychosis.

Abstract
We measured plasma free HVA and MHPG in 39 cases of psychosis or mania judged to be caused by antidepressant exacerbation of symptoms. A total of 24 of patients had been receiving selective serotonin reuptake inhibitors (SSRI's). The SSRI group showed a pattern of increased plasma HVA similar to a comparison group of patients with a psychotic/manic relapse secondary to medication non-compliance.
AuthorsFrank Fortunati, Carolyn Mazure, Adrian Preda, Rebecca Wahl, Malcolm Bowers Jr
JournalJournal of affective disorders (J Affect Disord) Vol. 68 Issue 2-3 Pg. 331-4 (Apr 2002) ISSN: 0165-0327 [Print] Netherlands
PMID12063160 (Publication Type: Journal Article)
Chemical References
  • Antidepressive Agents
  • Catecholamines
  • Serotonin Uptake Inhibitors
  • Homovanillic Acid
Topics
  • Adult
  • Antidepressive Agents (adverse effects, therapeutic use)
  • Bipolar Disorder (blood, chemically induced, diagnosis)
  • Catecholamines (blood)
  • Comorbidity
  • Female
  • Homovanillic Acid (blood)
  • Humans
  • Male
  • Middle Aged
  • Psychoses, Substance-Induced (blood, diagnosis)
  • Risk Factors
  • Selective Serotonin Reuptake Inhibitors (adverse effects, therapeutic use)

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