HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Iodine-123-metaiodobenzylguanidine scintigraphy of total cardiac adrenergic denervation in Brugada syndrome.

Abstract
A 22-year-old Japanese man with Brugada syndrome was resuscitated from cardiopulmonary arrest. In addition to the electrocardiographic evidence of the syndrome and the absence of apparent structural heart disease, no accumulation of iodine-123-metaiodobenzylguanidine (MIBG) was found anywhere throughout the heart. Thallium-201 (Tl) single photon emission computed tomography (SPECT) distribution showed no significant decrease in its uptake. To our knowledge, this is the first report that has demonstrated a homogeneous absence of cardiac accumulation of MIBG in Brugada syndrome.
AuthorsNaotsugu Oyama, Noriko Oyama, Hisashi Yokoshiki, Katsuhiko Satoh, Noriyoshi Katoh, Toshiyuki Hayashi, Kazuo Miyasaka, Akira Kitabatake
JournalJapanese heart journal (Jpn Heart J) Vol. 43 Issue 2 Pg. 183-6 (Mar 2002) ISSN: 0021-4868 [Print] Japan
PMID12025905 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Iodine Radioisotopes
  • Radiopharmaceuticals
  • 3-Iodobenzylguanidine
Topics
  • 3-Iodobenzylguanidine
  • Adult
  • Autonomic Nervous System Diseases (diagnostic imaging)
  • Bundle-Branch Block (diagnostic imaging)
  • Electrocardiography
  • Heart (diagnostic imaging, innervation)
  • Humans
  • Iodine Radioisotopes
  • Male
  • Radiopharmaceuticals
  • Syndrome
  • Tomography, Emission-Computed, Single-Photon
  • Ventricular Fibrillation (diagnosis)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: