Recent advances in hormonal male contraception.

Abstract

Hormones inhibit fertility in men by suppressing sperm production. Testosterone-enanthate induced azoospermia has proven to provide optimal contraceptive protection. Preliminary studies have shown that testosterone alone or androgen-progestin combinations induce profound sperm suppression in the Eastern and white populations, respectively. Thus, these regimens may represent viable options for male contraception. New long-acting androgen formulations represent a major advancement in this field, allowing for the development of more acceptable and effective regimens.

• Authors: M C Meriggiola, A Costantino, S Cerpolini
• Journal: Contraception (Contraception) Vol. 65 Issue 4 Pg. 269-72 (Apr 2002) ISSN: 0010-7824 [Print] United States
• PMID: 12020775 (Publication Type: Journal Article, Review)

Chemical References

• Androgens
• Antispermatogenic Agents
• Contraceptive Agents, Male
• Progestins
• Testosterone

Topics

• Androgens (administration & dosage)
• Antispermatogenic Agents (administration & dosage)
• Clinical Trials as Topic
• Contraceptive Agents, Male (administration & dosage, adverse effects)
• Humans
• Male
• Progestins (administration & dosage)
• Spermatogenesis (drug effects)
• Testosterone (administration & dosage)