Abstract |
Despite a large choice of drugs used for the treatment of chronic liver diseases, they often give only a temporary positive effect. In this study the effect of ursodeoxycholic acid on liver regeneration was investigated using the animal model of toxic hepatitis induced by anticonvulsive drug depackin, which is employed in infant neurology. The results of the study demonstrate stimulatory effect of ursodeoxycholic acid on regeneration process in animals' damaged liver, therefore its use may be recommended for the complex treatment of patients with toxic liver lesions.
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Authors | V V Sadovnikova, I V Sadovnikova, N L Ivanova |
Journal | Morfologiia (Saint Petersburg, Russia)
(Morfologiia)
Vol. 120
Issue 6
Pg. 63-5
( 2001)
ISSN: 1026-3543 [Print] Russia (Federation) |
Vernacular Title | Morfologicheskie izmeniia v pecheni krys pri toksicheskom medikamentoznom gepatite i stimuliatsii reparativnykh protsessov. |
PMID | 12016768
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Chemical and Drug Induced Liver Injury
(pathology, physiopathology)
- Disease Models, Animal
- Humans
- Liver Regeneration
- Rats
- Ursodeoxycholic Acid
(toxicity)
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