Total knee replacement in haemophilia.

Abstract

We believe that total knee replacement (TKR) is a safe and effective procedure for the management of haemophiliac joint arthropathy; however, the increased risk of infection and non-infective complications remain a cause for concern. TKR in haemophilic patients carries with it an increased risk of post-operative infection in comparison to non-haemophiliac patients. Those patients at particular risk are the HIV-positive haemophiliac patients whose CD4 count is less than 200 cells mm-3. The latest techniques have gone a long way to reducing the complication rate and to achieving results that match those of a similar non-haemophiliac population.

• Authors: N J Goddard, E C Rodriguez-Merchan, J D Wiedel
• Journal: Haemophilia : the official journal of the World Federation of Hemophilia (Haemophilia) Vol. 8 Issue 3 Pg. 382-6 (May 2002) ISSN: 1351-8216 [Print] England
• PMID: 12010438 (Publication Type: Journal Article, Review)

Topics

• Acquired Immunodeficiency Syndrome (complications)
• Arthroplasty, Replacement, Knee (adverse effects, statistics & numerical data)
• Hemarthrosis (prevention & control, surgery)
• Hemophilia A (complications, therapy, virology)
• Humans
• Treatment Outcome