Pulmonary actinomycosis followed by pericarditis and intractable pleuritis.

A case of pleuropericarditis caused by Actinomyces israelli is described. The patient first underwent left upper lobectomy because of pulmonary actinomycosis. Seven months later, cardiac tamponade developed. Culture of the bloody pericardial effusion resulted in positive growth of Actinomyces israeli. He was successfully treated with penicillin G, ampicillin, and minocyclin. However, right pleural effusion appeared two months later. Cultures of the effusion again yielded positive growth of the same bacteria. However, the strain had gained resistance to any antibiotics that had been effective before. Accordingly, pleurodesis with minocyclin was undertaken, which was fortunately effective for controlling the pleural effusion.
AuthorsNaofumi Shinagawa, Etsuro Yamaguchi, Toshiki Takahashi, Masaharu Nishimura
JournalInternal medicine (Tokyo, Japan) (Intern Med) Vol. 41 Issue 4 Pg. 319-22 (Apr 2002) ISSN: 0918-2918 [Print] Japan
PMID11993795 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Actinomyces (isolation & purification, pathogenicity)
  • Actinomycosis (complications, diagnostic imaging, pathology, therapy)
  • Adult
  • Anti-Bacterial Agents (therapeutic use)
  • Cardiac Tamponade (etiology)
  • Humans
  • Lung Diseases (complications, diagnostic imaging, pathology, therapy)
  • Male
  • Pericarditis (diagnostic imaging, etiology, pathology, therapy)
  • Pleurisy (diagnostic imaging, etiology, pathology, therapy)
  • Radiography, Thoracic

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