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The strategy for esophageal cancer control in high-risk areas of China.

Abstract
Even though the mortality from esophageal cancer has decreased during the last two decades nationwide in China, the mortality from esophageal cancer in high-risk areas is still at a high level. Moreover, the 5-year survival rate of patients with resectable esophageal cancer after treatment ranges between 20 and 30%, as majority of patients with esophageal cancer were diagnosed in late stages. Therefore, esophageal cancer control in high-risk areas in China remains a critical task. A strategy is proposed that the high-risk population would be screened by endoscopy with mucosal iodine staining and biopsy of all unstained lesions and diagnosis of severe dysplasia carcinoma in situ, and intra-mucosal carcinoma could be cured by radical mucosectomy. A pilot study showed that the strategy is feasible and cost-effective for the high prevalence of premalignant lesions and carcinomas in early stages. It would be expected that the mortality from esophageal cancer could be decreased in high-risk areas if the proposed strategy is carried out on a large scale.
AuthorsZhiwei Dong, Pingzhang Tang, Liandi Li, Guoqing Wang
JournalJapanese journal of clinical oncology (Jpn J Clin Oncol) Vol. 32 Suppl Pg. S10-2 (Mar 2002) ISSN: 0368-2811 [Print] England
PMID11959871 (Publication Type: Journal Article)
Topics
  • Biopsy
  • China (epidemiology)
  • Esophageal Neoplasms (diagnosis, mortality, prevention & control)
  • Esophagoscopy
  • Esophagus (pathology)
  • Health Promotion
  • Humans
  • Risk
  • Survival Rate

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