Abstract |
Even though the mortality from esophageal cancer has decreased during the last two decades nationwide in China, the mortality from esophageal cancer in high-risk areas is still at a high level. Moreover, the 5-year survival rate of patients with resectable esophageal cancer after treatment ranges between 20 and 30%, as majority of patients with esophageal cancer were diagnosed in late stages. Therefore, esophageal cancer control in high-risk areas in China remains a critical task. A strategy is proposed that the high-risk population would be screened by endoscopy with mucosal iodine staining and biopsy of all unstained lesions and diagnosis of severe dysplasia carcinoma in situ, and intra-mucosal carcinoma could be cured by radical mucosectomy. A pilot study showed that the strategy is feasible and cost-effective for the high prevalence of premalignant lesions and carcinomas in early stages. It would be expected that the mortality from esophageal cancer could be decreased in high-risk areas if the proposed strategy is carried out on a large scale.
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Authors | Zhiwei Dong, Pingzhang Tang, Liandi Li, Guoqing Wang |
Journal | Japanese journal of clinical oncology
(Jpn J Clin Oncol)
Vol. 32 Suppl
Pg. S10-2
(Mar 2002)
ISSN: 0368-2811 [Print] England |
PMID | 11959871
(Publication Type: Journal Article)
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Topics |
- Biopsy
- China
(epidemiology)
- Esophageal Neoplasms
(diagnosis, mortality, prevention & control)
- Esophagoscopy
- Esophagus
(pathology)
- Health Promotion
- Humans
- Risk
- Survival Rate
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