From 1958 approximately 1998, a total of 74 patients with benign and malignant
thecoma were retrospectively analyzed.
RESULTS: The reviewed diagnosis were 8 patients with malignant
thecoma, 66 patients were benign
thecoma. Nine of 66 patients with benign
thecoma appeared cell proliferative activity. The mean age was 52 years. The most frequent symptoms were abdominal-pelvic masses (56.8%), metromenorrhagia and abnormal
vaginal bleeding, other symptoms were
abdominal pain,
infertility followed. Twenty-two of 66 patients had
ascites, only 1 patient with
ascites and
hydrothorax simultaneously. Thirty-nine patients with diseases which associate with excessive estrogenic stimulation, including 1 endometrial
adenocarcinoma and 1 endometrial dysplasia and other diseases such as:
myoma;
endometrial hyperplasia and
polyp. Fifteen patients with benign
thecoma were evaluated blood serum CA(125), the CA(125) were elevated in 9 of 15 patients. In 2 of 9 patients with cell proliferative activity, the
tumors invaded adjacent tissues or relapsed, after received operation and pelvic
radiotherapy, they are alive 11 years and 27 years respectively. Among 8 patients with malignant
thecoma, 4 patients without postoperation
therapy or with non-standard
chemotherapy died in 2 years postoperation, the other 4 patients received operation, postoperational
radiotherapy or (and)
chemotherapy, 1 of 4 patients died of irradiation intestinal fistule 4 years later; two patients are alive without disease more than 10 years, another one for 2 years.
CONCLUSIONS: