Abstract | OBJECTIVE: DESIGN: Prospective, comparative, experimental study. SETTING: Laboratory at a university hospital. SUBJECTS: Twenty-seven male Wistar rats, age 6-7 wks, weighing 160-170 g. INTERVENTIONS: Three groups of animals were studied: a control group (n = 8) receiving physiologic saline, a tissue factor-treated group (n = 11) receiving tissue factor 3.75 units/kg, and a lipopolysaccharide-treated group (n = 8) receiving lipopolysaccharide 30 mg/kg; each group sustained infusion for 4 hrs via the tail vein. MEASUREMENTS AND MAIN RESULTS: CONCLUSION:
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Authors | Hidesaku Asakura, Yukio Suga, Keiji Aoshima, Yasuo Ontachi, Tomoe Mizutani, Minori Kato, Masanori Saito, Eriko Morishita, Masahide Yamazaki, Akiyoshi Takami, Ken-ichi Miyamoto, Shinji Nakao |
Journal | Critical care medicine
(Crit Care Med)
Vol. 30
Issue 1
Pg. 161-4
(Jan 2002)
ISSN: 0090-3493 [Print] United States |
PMID | 11902257
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Fibrin Fibrinogen Degradation Products
- Lipopolysaccharides
- antithrombin III-protease complex
- fibrin fragment D
- Antithrombin III
- Fibrin
- Thromboplastin
- Peptide Hydrolases
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Topics |
- Animals
- Antithrombin III
- Disease Models, Animal
- Disseminated Intravascular Coagulation
(etiology, physiopathology)
- Fibrin
(analysis)
- Fibrin Fibrinogen Degradation Products
(analysis)
- Hemostasis
(physiology)
- Kidney
(pathology)
- Lipopolysaccharides
- Male
- Peptide Hydrolases
(blood)
- Prospective Studies
- Rats
- Rats, Wistar
- Thromboplastin
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