HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Factors affecting the outcome of patients with splenic trauma.

Abstract
This is a report of 546 consecutive patients with penetrating and blunt splenic trauma seen over a 17 1/2-year period (1980-1997). The etiology of the splenic injuries and the associated mortality rates were: blunt injuries 45 of 298 (15%), gunshot wounds 48 of 199 (24%), and stab wounds four of 49 (8%). The overall mortality rate was 97 of 546 (18%). The most significant risk factors for death were all associated with major blood loss: transfusion requirements > or = 6 units of blood, low initial operating room blood pressure, associated abdominal vascular injuries, and performance of a thoracotomy. The two most important organs injured in conjunction with the spleen that were significant predictors of postoperative infectious complications were colon and pancreas. The need for splenectomy was most significantly correlated with higher grades of splenic injury especially grades IV and V. The evolution in management of blunt splenic trauma has led to a significant improvement in splenic preservation and avoidance of laparotomy for many patients. Operative splenic salvage is reduced in patients subjected to laparotomy who are candidates for nonoperative treatment. Improved results with splenic injury should be obtained by rapid control of bleeding. This may require more liberal criterial in selecting patients with splenic trauma for early operative treatment.
AuthorsArthur M Carlin, James G Tyburski, Robert F Wilson, Christopher Steffes
JournalThe American surgeon (Am Surg) Vol. 68 Issue 3 Pg. 232-9 (Mar 2002) ISSN: 0003-1348 [Print] United States
PMID11893100 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adult
  • Age Distribution
  • Analysis of Variance
  • Female
  • Humans
  • Injury Severity Score
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Probability
  • Prognosis
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Sex Distribution
  • Spleen (injuries)
  • Splenectomy (methods)
  • Survival Rate
  • Wounds, Nonpenetrating (diagnosis, epidemiology, surgery)
  • Wounds, Penetrating (diagnosis, epidemiology, surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: