HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Type 1 diabetes mellitus and epilepsia partialis continua in a 6-year-old boy with elevated anti-GAD65 antibodies.

Abstract
A 6-year-old boy presented with epilepsia partialis continua 6 months after diagnosis of type 1 diabetes. Anti-glutamic acid decarboxylase 65 antibodies were found in his serum and cerebrospinal fluid. Anti-epileptic agents did not improve his seizures. High-dose steroids, plasmapheresis, and intravenous immunoglobulin resulted in decreased anti-glutamic acid decarboxylase 65 antibody levels and resolution of his seizures.
AuthorsJennifer A Olson, Donald M Olson, Christy Sandborg, Steven Alexander, Bruce Buckingham
JournalPediatrics (Pediatrics) Vol. 109 Issue 3 Pg. E50 (Mar 2002) ISSN: 1098-4275 [Electronic] United States
PMID11875178 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Autoantibodies
  • Immunoglobulins, Intravenous
  • Isoenzymes
  • Prednisolone
  • Glutamate Decarboxylase
  • glutamate decarboxylase 2
Topics
  • Autoantibodies (blood)
  • Brain (pathology)
  • Child
  • Combined Modality Therapy
  • Diabetes Mellitus, Type 1 (immunology)
  • Epilepsia Partialis Continua (immunology, therapy)
  • Glutamate Decarboxylase (immunology)
  • Humans
  • Immunoglobulins, Intravenous (therapeutic use)
  • Isoenzymes (immunology)
  • Male
  • Plasmapheresis
  • Prednisolone (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: