Abstract | BACKGROUND: OBJECTIVE: DESIGN: Twelve healthy men were studied on 4 separate occasions. On 2 occasions, the subjects received a high-fat evening meal (62% of energy from fat) and on the other 2 occasions the subjects received a low-fat evening meal (16% of energy from fat). The morning after each meal the subjects were administered either an oral-fat-tolerance test or an oral- glucose-tolerance test. Plasma samples were analyzed for glucose, insulin, fatty acids, 3-hydroxybutyrate, triacylglycerol, pancreatic polypeptide, peptide YY, and cholecystokinin. Postchallenge data were analyzed by two-way analysis of variance with interaction and fasting concentrations analyzed by repeated-measures analysis of variance. RESULTS: CONCLUSIONS: The present study showed that the effects of high-fat and high- carbohydrate evening meals persist at least overnight and suggests that knowledge of recent dietary history is essential to the effective design of metabolic studies.
|
Authors | M Denise Robertson, R Alex Henderson, Gunn E Vist, R David E Rumsey |
Journal | The American journal of clinical nutrition
(Am J Clin Nutr)
Vol. 75
Issue 3
Pg. 505-10
(Mar 2002)
ISSN: 0002-9165 [Print] United States |
PMID | 11864856
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Blood Glucose
- Dietary Carbohydrates
- Dietary Fats
- Fatty Acids
- Fatty Acids, Nonesterified
- Gastrointestinal Hormones
- Triglycerides
- Peptide YY
- Pancreatic Polypeptide
- Cholecystokinin
- 3-Hydroxybutyric Acid
|
Topics |
- 3-Hydroxybutyric Acid
(blood)
- Adult
- Analysis of Variance
- Area Under Curve
- Blood Glucose
(analysis)
- Cholecystokinin
(blood)
- Dietary Carbohydrates
(administration & dosage, metabolism)
- Dietary Fats
(administration & dosage, metabolism)
- Energy Metabolism
- Fasting
(blood)
- Fatty Acids
(blood)
- Fatty Acids, Nonesterified
(blood)
- Gastrointestinal Hormones
(blood)
- Glucose Tolerance Test
- Humans
- Insulin Resistance
- Male
- Pancreatic Polypeptide
(blood)
- Peptide YY
(blood)
- Postprandial Period
(physiology)
- Triglycerides
(blood)
|