Influence of root canal dressings and sealers on repair of apical periodontitis after endodontic treatment.

Abstract

OBJECTIVE:

The objective of this study was to evaluate the histopathologic response of periapical tissues after root canal treatment of necrotic dog teeth with chronic apical periodontitis by using 2 calcium hydroxide-based root canal dressings and 2 root canal sealers.

STUDY DESIGN:

Seventy-eight root canals were instrumented by using 5.25% sodium hypochlorite as the irrigating solution, after which a calcium hydroxide paste (Calen/PMCC or Calasept) was placed for 30 days as a dressing. The root canals were then filled by using cold lateral gutta-percha condensation and an endodontic sealer (Sealapex or AH Plus). After 360 days, the animals were killed by anesthetic overdose; then, the teeth were histologically prepared, sectioned, and stained with hematoxylin and eosin for optical microscopic analysis of apical and periapical tissue repair.

RESULTS:

Statistical analysis showed that the poorest histopathologic results were observed in the Calasept/AH Plus group and that the Sealapex sealer overall resulted in better apical repair than the AH Plus sealer. The histopathologic results of Calen/PMCC paste with both AH Plus and Sealapex and Calasept paste with only Sealapex were statistically similar but were different from the results of Calasept with AH Plus.

CONCLUSIONS:

The results of this study in the dog showed differences in apical and periapical tissue repair of teeth with chronic apical periodontitis by using 2 calcium hydroxide root canal dressings and 2 sealers. More research is necessary to determine the best combination of dressings and sealers.

• Authors: Fábio Luiz Camargo Villela Berbert, Mário Roberto Leonardo, Léa Assed Bezerra Silva, Mário Tanomaru Filho, Clóvis Monteiro Bramante
• Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics (Oral Surg Oral Med Oral Pathol Oral Radiol Endod) Vol. 93 Issue 2 Pg. 184-9 (Feb 2002) ISSN: 1079-2104 [Print] United States
• PMID: 11862209 (Publication Type: Comparative Study, Evaluation Study, Journal Article)

Chemical References

• Drug Combinations
• Epoxy Resins
• Root Canal Filling Materials
• Root Canal Irrigants
• Salicylates
• calcium hydroxide, calcium chloride, potassium chloride, sodium bicarbonate, sodium chloride drug combination
• calen
• epoxy resin-based root canal sealer
• Sealapex
• Sodium Chloride
• Potassium Chloride
• Sodium Bicarbonate
• Calcium Chloride
• Calcium Hydroxide

Topics

• Animals
• Calcium Chloride
• Calcium Hydroxide (pharmacology)
• Dogs
• Drug Combinations
• Epoxy Resins (pharmacology)
• Periapical Periodontitis (therapy)
• Periapical Tissue (drug effects)
• Potassium Chloride
• Random Allocation
• Root Canal Filling Materials (pharmacology)
• Root Canal Irrigants (pharmacology)
• Root Canal Therapy (methods)
• Salicylates (pharmacology)
• Sodium Bicarbonate
• Sodium Chloride
• Statistics, Nonparametric
• Wound Healing (drug effects)