Abstract | PURPOSE: METHODS: RESULTS: Five patients (71.5%) were men and two (28.5%) were women. The average age at the time of surgery was 32.7 +/- 10.9 years (range, 20-45). Mean follow-up after last surgery was 8.9 +/- 3.2 months (range, 6-14). The average epithelial healing time was 24.6 +/- 17.3 days (range, 3-45). At the end of the follow-up period, visual acuity improved in all eyes, inflammation subsided, and the subjective complaints decreased remarkably. CONCLUSION: AMT with nonpreserved amniotic membrane promoted epithelial healing, reduced surface inflammation, increased patient comfort, and decreased the extent and severity of vascularization when used in patients with acute chemical burns. When used in limbal stem cell deficiency owing to past chemical burns, AMT alone or in combination with LAT aided in ocular surface reconstruction. Infectious, inflammatory, or toxic/ allergic reactions were not encountered in any patient owing to the use of nonpreserved amniotic membrane. Further studies are required to establish the safety and efficacy of preserved and nonpreserved AMT in ocular surface reconstruction.
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Authors | Omür O Uçakhan, Gültekin Köklü, Esin Firat |
Journal | Cornea
(Cornea)
Vol. 21
Issue 2
Pg. 169-72
(Mar 2002)
ISSN: 0277-3740 [Print] United States |
PMID | 11862088
(Publication Type: Journal Article)
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Topics |
- Acute Disease
- Adult
- Amnion
(transplantation)
- Burns, Chemical
(pathology, surgery)
- Chronic Disease
- Corneal Diseases
(pathology, surgery)
- Epithelial Cells
(transplantation)
- Eye Burns
(chemically induced, pathology, surgery)
- Female
- Follow-Up Studies
- Humans
- Limbus Corneae
(cytology)
- Male
- Middle Aged
- Safety
- Stem Cell Transplantation
- Tissue Preservation
- Transplantation, Autologous
- Wound Healing
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