Subcarinal bronchogenic cyst with high carbohydrate antigen 19-9 production.

Abstract

In a rare case of bronchogenic cyst with high carbohydrate antigen (CA) 19-9 production, a 57-year-old man with coughing and chest pain was diagnosed with a subcarinal mediastinal tumor. Fiberoptic bronchoscopy showed an erosive mucosal lesion overlying the area of extrinsic compression at the membranous of the right mainstem bronchus. Serum carbohydrate antigen 19-9 was elevated at 1300 U/ml. Thoracotomy showed an encapsulated cyst tightly adhering to the right main bronchus. The cyst was extirpated after ablation at the adherent cystic wall by electrocautery. Although intracystic carbohydrate antigen 19-9 concentration was very high, serum carbohydrate antigen 19-9 and bronchoscopic findings returned to normal postoperatively. The histological diagnosis was consistent with a bronchogenic cyst and carbohydrate antigen 19-9 could be immunohistochemically demonstrated within its epithelium.

• Authors: Kan Okabayashi, Akira Motohiro, Hitoshi Ueda, Kaoru Ondo, Katsunobu Kawahara, Takayuki Shirakusa
• Journal: The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi (Jpn J Thorac Cardiovasc Surg) Vol. 50 Issue 1 Pg. 46-8 (Jan 2002) ISSN: 1344-4964 [Print] Japan
• PMID: 11855101 (Publication Type: Case Reports, Journal Article)

Chemical References

• CA-19-9 Antigen

Topics

• Bronchogenic Cyst (diagnosis, immunology, surgery)
• Bronchoscopy
• CA-19-9 Antigen (blood)
• Humans
• Male
• Middle Aged
• Radiography, Thoracic