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Necrotic seminoma of the testis: establishing the diagnosis with Masson trichrome stain and immunostains.

Abstract
We describe an infarcted mass in the testis containing "ghost" cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.
AuthorsBarbara D Florentine, Arno A Roscher, Jerry Garrett, Nancy E Warner
JournalArchives of pathology & laboratory medicine (Arch Pathol Lab Med) Vol. 126 Issue 2 Pg. 205-6 (Feb 2002) ISSN: 0003-9985 [Print] United States
PMID11825120 (Publication Type: Case Reports, Journal Article)
Topics
  • Humans
  • Male
  • Middle Aged
  • Necrosis
  • Seminoma (diagnosis, pathology)
  • Staining and Labeling (methods)
  • Testicular Neoplasms (diagnosis, pathology)

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