Abstract | BACKGROUND: MATERIAL AND METHODS: From September 1998 until July 2000, a total of 27 patients underwent LDLT at USC University Hospital and Los Angeles Children's Hospital. There were 12 children with the median age of 10 months (4-114) and 15 adults with the median age of 56 years (35-65). The most common indication for transplantation was biliary atresia for children and hepatitis C for adults. RESULTS: All donors did well postoperatively; the median postoperative stay was five days (5-7) for left lateral segmentectomy and seven days (4-12) for lobar donation. None of the donors required blood transfusion, re-operation or postoperative invasive procedure. However, five of them (18%) experienced minor complications. The survival rate in pediatric patients was 100% and only one graft was lost at nine months due to rejection. Two adult recipients died in the postoperative period, one from graft non-function and one from necrotizing fascitis. 37% of adult recipients experienced postoperative complications, mainly related to biliary reconstruction. Also 26% of the recipients underwent reoperation for some of these complications. CONCLUSION: LDLT is an excellent alternative to cadaveric transplantation with excellent results in the pediatric population. However, in adult patients it still carries a significant complication rate and it should be used with caution.
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Authors | N Jabbour, Y Genyk, R Mateo, C Peyre, R V Patel, D Thomas, P Ralls, S Palmer, G Kanel, R R Selby |
Journal | Acta chirurgica Belgica
(Acta Chir Belg)
2001 Sep-Oct
Vol. 101
Issue 5
Pg. 220-3
ISSN: 0001-5458 [Print] England |
PMID | 11758104
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- California
- Child
- Child, Preschool
- Female
- Graft Survival
- Hospitals, University
- Humans
- Infant
- Length of Stay
- Liver Diseases
(mortality, surgery)
- Liver Transplantation
- Living Donors
- Male
- Middle Aged
- Retrospective Studies
- Treatment Outcome
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