[Etiology of community-acquired pneumonia in ambulatory patients. Usefulness of a diagnostic investigation protocol using detection of Streptococcus pneumoniae and Legionella pneumophila antigens in urine samples].

Abstract

BACKGROUND:

To determine the etiology of community-acquired pneumonia (CAP) in ambulatory patients and to assess the efficiency of a diagnostic protocol by using tests to detect bacterial antigens in urine samples.

PATIENTS AND METHOD:

One-year prospective study that included blood and sputum cultures, serologic studies, and detection of Legionella pneumophila and Streptococcus pneumoniae urinary antigens.

RESULTS:

49 patients were recruited and an etiological diagnosis was attained in 34 (69%). Microorganisms most frequently isolated were S. pneumoniae (12 cases), Mycoplasma pneumoniae (7), Haemophilus influenzae (4), respiratory viruses (4) and Coxiella burnetii (3 cases).

CONCLUSIONS:

By means of a non-invasive protocol with urinary antigen tests, a microbial etiology can be established in two thirds of patients with mild CAP. S. pneumoniae is the main cause of mild CAP.

• Authors: C Mirete Ferrer, F Gutiérrez Rodero, J C Rodríguez Díaz, G Royo García, C Shum Fhunk, A Martín Hidalgo
• Journal: Medicina clinica (Med Clin (Barc)) Vol. 117 Issue 17 Pg. 657-9 (Nov 24 2001) ISSN: 0025-7753 [Print] Spain
• Vernacular Title: Etiología de la neumonía adquirida en la comunidad tratada ambulatoriamente. Utilidad de un protocolo diagnóstico con pruebas microbiológicas convencionales y detección de antígenos de Streptococcus pneumoniae y Legionella pneumophila en orina.
• PMID: 11734171 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antigens, Bacterial

Topics

• Adolescent
• Adult
• Antigens, Bacterial (urine)
• Community-Acquired Infections (diagnosis, urine)
• Female
• Humans
• Legionella pneumophila (immunology)
• Legionnaires' Disease (diagnosis, urine)
• Male
• Middle Aged
• Pneumonia, Bacterial (diagnosis, urine)
• Pneumonia, Pneumococcal (diagnosis, urine)
• Prospective Studies
• Streptococcus pneumoniae (immunology)