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Secondary metabolic changes in fibroblasts from six patients with hereditary lactic acidosis.

Abstract
Studies on fibroblasts from patients with lactic acidosis of different causes showed secondary metabolic changes in pathways of glucose metabolism. These secondary changes may be important clues to the diagnosis of the many different types of hereditary lactic acidosis.
AuthorsO Borud, J H Strømme
JournalJournal of inherited metabolic disease (J Inherit Metab Dis) Vol. 1 Issue 4 Pg. 161-2 ( 1978) ISSN: 0141-8955 [Print] United States
PMID117250 (Publication Type: Journal Article)
Chemical References
  • Lactates
  • Pyruvates
  • Glucose
Topics
  • Acidosis (enzymology)
  • Carbohydrate Metabolism, Inborn Errors (enzymology)
  • Cells, Cultured
  • Child, Preschool
  • Citric Acid Cycle
  • Fibroblasts (metabolism)
  • Glucose (metabolism)
  • Glycolysis
  • Humans
  • Infant
  • Infant, Newborn
  • Lactates (metabolism)
  • Pyruvates (metabolism)

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