Abstract | OBJECTIVE: The purpose of this study was to determine risk factors associated with intrauterine fetal demise in fetuses with unexplained echogenic bowel that is diagnosed in the second trimester. STUDY DESIGN: RESULTS: One hundred fifty-six fetuses met the inclusion criteria. There were 9 cases of intrauterine fetal demise and 147 live born control fetuses. The median gestational age of intrauterine fetal demise was 22.0 weeks (range, 17-39 weeks). Intrauterine growth restriction occurred more frequently in cases of intrauterine fetal demise than in live born infants (22.2% vs 0.7%; P =.009), as did oligohydramnios (44.4% vs 2.0%; P <.001) and elevated maternal serum alpha-fetoprotein levels (80.0% vs 7.7%; P: =.001). With the use of logistic regression analysis, elevated maternal serum alpha-fetoprotein was the strongest independent risk factor that was associated with intrauterine fetal demise (odds ratio, 39.48; 95% CI, 11.04%-141.25%). CONCLUSION:
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Authors | H B Al-Kouatly, S T Chasen, A K Karam, R Ahner, F A Chervenak |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 185
Issue 5
Pg. 1039-43
(Nov 2001)
ISSN: 0002-9378 [Print] United States |
PMID | 11717629
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
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Topics |
- Adult
- Case-Control Studies
- Female
- Fetal Death
(diagnostic imaging, epidemiology)
- Humans
- Incidence
- Infant Mortality
- Infant, Newborn
- Intestines
(diagnostic imaging, embryology)
- Pregnancy
- Retrospective Studies
- Risk Factors
- Ultrasonography, Prenatal
- alpha-Fetoproteins
(analysis)
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