Oversized corneal grafts for corneal opacities with iridocorneal adhesions.

Abstract

OBJECTIVE:

To evaluate the efficacy of 1-mm oversized corneal grafts in patients with acquired corneal opacities and extensive peripheral iridocorneal adhesions.

DESIGN:

Prospective noncomparative case series.

PARTICIPANTS:

Twenty patients (20 eyes) aged 15 years or older with unilateral or bilateral corneal opacification and a shallow anterior chamber.

INTERVENTION:

Penetrating keratoplasty was performed with donor corneal buttons oversized by 1 mm.

MAIN OUTCOME MEASURES:

The various parameters evaluated were visual acuity, graft clarity, keratometry, anterior chamber depth, intraocular pressure, and spherical equivalent refraction 12 months after surgery.

RESULTS:

The keratoplasties were performed in 15 eyes with a corneo-iridic scar after infectious keratitis (75%) and 5 eyes with failed graft (25%). At the final follow-up, a clear graft was achieved in 17 eyes (85%), and 14 eyes (70%) achieved a best-corrected visual acuity of 6/12 or better. Three of the grafts failed because of rejection. The average keratometry was 44.1 +/- 1.0 diopters (D), and the mean spherical equivalent was -3.23 +/- 2.86 D. The oversized grafts provided a mean anterior chamber depth of 2.36 +/- 0.42 mm, and the mean intraocular pressure at the 12 month follow-up was 16.38 +/- 2.09 mmHg.

CONCLUSIONS:

Corneal grafts oversized by 1 mm provide adequate anterior chamber depth and reduce the risk of peripheral anterior synechiae and secondary glaucoma in patients with corneal opacities and extensive peripheral iridocorneal adhesions.

• Authors: R B Vajpayee, T Dada, M Ray, R Tandon, A Sethi, K Turaka
• Journal: Ophthalmology (Ophthalmology) Vol. 108 Issue 11 Pg. 2026-8 (Nov 2001) ISSN: 0161-6420 [Print] United States
• PMID: 11713073 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Anterior Chamber (anatomy & histology)
• Cornea (anatomy & histology)
• Corneal Opacity (surgery)
• Female
• Glaucoma (prevention & control)
• Graft Survival
• Humans
• Intraocular Pressure
• Iris Diseases (prevention & control, surgery)
• Keratoplasty, Penetrating (methods)
• Male
• Middle Aged
• Prospective Studies
• Refraction, Ocular
• Tissue Adhesions (prevention & control, surgery)
• Tissue Donors
• Visual Acuity