Abstract | BACKGROUND: MATERIALS AND METHODS: The binding status of ML-I, -II and -III was histochemically assessed in 100 malignant melanomas and correlated with metastasis in a 10 year follow-up period. Furthermore, the staining intensity of the three MLs, scored from negative (-) to very intense (+ + +), was evaluated. RESULTS: Kaplan-Meier analsis revealed that very intense binding (+ + +) of ML-I was positively-correlated with metastasis (p=0.044). CONCLUSION:
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Authors | A Thies, U Pfüller, M Schachner, H P Horny, I Molls, U Schumacher |
Journal | Anticancer research
(Anticancer Res)
2001 Jul-Aug
Vol. 21
Issue 4B
Pg. 2883-7
ISSN: 0250-7005 [Print] Greece |
PMID | 11712781
(Publication Type: Journal Article)
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Chemical References |
- Adjuvants, Immunologic
- Antineoplastic Agents, Phytogenic
- Lectins
- Plant Preparations
- Plant Proteins
- Ribosome Inactivating Proteins, Type 2
- Toxins, Biological
- mistletoe lectin I
- ribosome inactivating protein, Viscum
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Topics |
- Adjuvants, Immunologic
(pharmacology)
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Agents, Phytogenic
(metabolism)
- Disease-Free Survival
- Female
- Follow-Up Studies
- Humans
- Killer Cells, Natural
(drug effects, pathology)
- Lectins
(metabolism)
- Life Tables
- Male
- Melanoma
(metabolism, pathology, surgery)
- Middle Aged
- Neoplasm Metastasis
- Plant Preparations
- Plant Proteins
- Prognosis
- Ribosome Inactivating Proteins, Type 2
- Skin Neoplasms
(metabolism, pathology, surgery)
- Toxins, Biological
(metabolism, pharmacology)
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