Idiopathic hypertrophic subaortic stenosis presenting as cough syncope.

Abstract

In a patient with idiopathic hypertrophic subaortic stenosis, syncope developed as a result of a sustained decrease in aortic pressure induced by severe cough paroxysms. Treatment with propranolol was effective in abolishing the syncopal episodes, by reducing the post-tussive gradient and facilitating a more rapid return to normal of aortic pressure. Post-tussive syncope in IHSS may result from both an unusually strong cough paroxysm and augmented left ventricular outflow obstruction consequent to reflex sympathetic stimulation.

• Authors: C W White, T J Zimmerman, M Ahmad
• Journal: Chest (Chest) Vol. 68 Issue 2 Pg. 250-3 (Aug 1975) ISSN: 0012-3692 [Print] United States
• PMID: 1171002 (Publication Type: Journal Article)

Chemical References

• Propranolol

Topics

• Cardiomyopathy, Hypertrophic (complications, diagnosis)
• Cough (complications, drug therapy)
• Humans
• Hypertension (diagnosis)
• Male
• Middle Aged
• Propranolol (therapeutic use)
• Syncope (etiology)