High-dose vitamin B(6) treatment in West syndrome.

Abstract

Approximately 10-30% of patients with West syndrome respond to high-dose vitamin B(6) treatment. The response to vitamin B(6) is rapid; seizures disappear within the first 2 weeks of treatment. Mild side effects, such as gastrointestinal symptoms and liver dysfunction, are observed in 40-70%, but these resolve after discontinuation or a reduction of the dosage of vitamin B(6). High-dose vitamin B(6) treatment is useful as a first line agent in treating West syndrome.

• Authors: Y Toribe
• Journal: Brain & development (Brain Dev) Vol. 23 Issue 7 Pg. 654-7 (Nov 2001) ISSN: 0387-7604 [Print] Netherlands
• PMID: 11701272 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Vitamin B 6

Topics

• Electrocardiography
• Female
• Humans
• Infant, Newborn
• Spasms, Infantile (diagnosis, drug therapy)
• Vitamin B 6 (administration & dosage, adverse effects)