[Comparative clinical efficacy and tolerance of cefuroxime axetil (zinnat) and ceftibuten (cedex) in patients with acute sinusitis].

Abstract

The aim of the study was to substantiate clinically and microbiologically administration of such oral cephalosporins as cefuroxime axetil and ceftibuten in acute sinusitis. The spectrum of causative agents of acute sinusitis was determined, most common pathogens were identified and their sensitivity to antibiotics was tested. The conclusion is made that cephalosporins of the II-III generation meet the requirements to antibacterial drugs for treatment of acute sinusitis.

• Authors: I V Otvagin, E I Kamanin, L S Strachunskiĭ, S N Kozlov
• Journal: Vestnik otorinolaringologii (Vestn Otorinolaringol) Issue 5 Pg. 29-32 ( 2001) ISSN: 0042-4668 [Print] Russia (Federation)
• Vernacular Title: Sravnitel'naia otsenka klinicheskoĭ éffektivnosti i perenosimosti tsefuroksim aksetila (zinnata) i tseftibutena (tsedeksa) u patsientov s ostrym sinusitom.
• PMID: 11699089 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Cephalosporins
• Ceftibuten
• Cefuroxime
• cefuroxime axetil

Topics

• Acute Disease
• Adult
• Ceftibuten
• Cefuroxime (analogs & derivatives, therapeutic use)
• Cephalosporins (therapeutic use)
• Drug Tolerance
• Female
• Humans
• Male
• Sinusitis (drug therapy)
• Treatment Outcome