A-waves in patients with novel hereditary motor and sensory neuropathy Lom.

Abstract

OBJECTIVES:

To determine A-waves of a family with autosomal recessive form of demyelinatig hereditary motor and sensory neuropathy Lom (HMSNL).

METHODS:

A-waves were investigated during conventional F-wave study of family members with HMSNL which had genetic testing.

RESULTS:

During routine F-wave studies A-waves were observed in all tested nerves. They appeared between M-responses and F-wave. The A-waves were with low amplitude, shorter duration and constant shape and latency than F-waves. They appeared independently of F-waves. A-waves were more often recorded as multiple waves in lower and upper extremities. More than three A-waves per nerve were found mostly in ulnar and facial nerves. In 16 cases A-waves were found in the absence of F-waves.

CONCLUSION:

It is assumed that the A-waves could be seen as additional signs of pathology because they were not observed in unaffected members of the family and in healthy subjects.

• Authors: A S Alexandrov, L G Christova, B A Ishpekova
• Journal: Acta physiologica et pharmacologica Bulgarica (Acta Physiol Pharmacol Bulg) Vol. 26 Issue 1-2 Pg. 55-8 ( 2001) ISSN: 0323-9950 [Print] Bulgaria
• PMID: 11693402 (Publication Type: Journal Article)

Topics

• Action Potentials
• Adolescent
• Adult
• Child
• Electromyography
• Female
• Hereditary Sensory and Motor Neuropathy (physiopathology)
• Humans
• Male
• Muscles (physiopathology)
• Reaction Time