Abstract |
The effectiveness of bread fortified with iron bis-glycinate chelate for the control of iron deficiency and iron deficiency anemia was evaluated in 89 preschool children from families of low socioeconomic level attending 2 day nurseries of the Sao Paulo City Council. During the intervention's time of 6 months the children received besides their usual center's diet, a daily supplement of two sweet rolls fortified with 2 mg each of iron from the chelate for a total daily iron intake of 4 mg. After six months of intervention there was a significant decrease in the prevalence of iron deficiency anemia from 62 to 22%. There was a mean hemoglobin improvement of 1.1 g/dL, and in children with initial hemoglobin levels < 11 g/dL the mean increase in hemoglobin was 1.42 g/dL. The total mean plasma ferritin values increased from 11.34 to 20.2 micrograms/L, and in those children originally iron depleted the ferritin values normalized. A significant increase in the "z" score for weight/height was also observed. We concluded that the use of sweet rolls fortified with 2 mg of iron from the bis-glycinate chelate is highly effective for the control of iron deficiency and iron deficiency anemia in young children.
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Authors | E Giorgini, M Fisberg, R A De Paula, A M Ferreira, J Valle, J A Braga |
Journal | Archivos latinoamericanos de nutricion
(Arch Latinoam Nutr)
Vol. 51
Issue 1 Suppl 1
Pg. 48-53
(Mar 2001)
ISSN: 0004-0622 [Print] Venezuela |
PMID | 11688082
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Ferrous Compounds
- Hemoglobins
- Iron Chelating Agents
- bis-glycino iron II
- Ferritins
- Glycine
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Topics |
- Anemia, Iron-Deficiency
(epidemiology, prevention & control)
- Anthropometry
- Brazil
(epidemiology)
- Bread
- Child
- Child, Preschool
- Female
- Ferritins
(blood)
- Ferrous Compounds
(therapeutic use)
- Food, Fortified
- Glycine
(analogs & derivatives, therapeutic use)
- Hemoglobins
(analysis)
- Humans
- Iron Chelating Agents
(therapeutic use)
- Iron Deficiencies
- Male
- Prevalence
- Treatment Outcome
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