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Plasmapheresis in fulminant acute disseminated encephalomyelitis.

Abstract
We report an 11-year-old girl with acute disseminated encephalomyelitis (ADEM) who developed respiratory failure and coma despite the use of corticosteroid and intravenous immunoglobulin. We performed plasmapheresis four times, which improved her level of consciousness, hyperesthesia, external ophthalmoplegia and muscle weakness, and led to the normalization of brain and spinal cord MRI. Plasmapheresis might be an effective treatment in cases of fulminant ADEM.
AuthorsR Miyazawa, A Hikima, Y Takano, H Arakawa, T Tomomasa, A Morikawa
JournalBrain & development (Brain Dev) Vol. 23 Issue 6 Pg. 424-6 (Oct 2001) ISSN: 0387-7604 [Print] Netherlands
PMID11578855 (Publication Type: Case Reports, Journal Article)
Topics
  • Child
  • Encephalomyelitis, Acute Disseminated (pathology, therapy)
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Plasmapheresis

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