Abstract | BACKGROUND: In severe chemical and thermal eye burns the limbal stem cells, which are important for the regeneration of the corneal epithelium, are lost. In our retrospective study two questions were investigated: 1) is it possible to restore the limbal region by transplantation of large diameter keratoplasties 2) has the time of transplantation an influence on the clinical outcome. PATIENTS AND METHOD: In a retrospective study the outcome of 48 eyes (43 patients) with severe chemical and thermal burns were analysed. Large diameter (11 - 12 mm) penetrating keratoplasties were performed between 1987 and 1996. Complete limbal deficiency was present in 17 eyes, while 31 eyes had developed sterile corneal ulceration. According to the time of transplantation three different groups were distinguished. Group I (early keratoplasty, n=24): transplantation within 3 months after the accident (mean: 26 days). Group II (intermediate keratoplasty, n=13): transplantation between 4 - 18 months after the burn (mean: 190 days). Group III (late keratoplasty, n=11): surgery more than 18 months after the injury (mean: 36.6 months). RESULTS: CONCLUSION:
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Authors | R Kuckelkorn, G Keller, C Redbrake |
Journal | Klinische Monatsblatter fur Augenheilkunde
(Klin Monbl Augenheilkd)
Vol. 218
Issue 8
Pg. 542-52
(Aug 2001)
ISSN: 0023-2165 [Print] Germany |
Vernacular Title | Langzeitergebnisse der Keratoplastik mit grossem Durchmesser von 11 - 12 mm bei schwerstverätzten und verbrannten Augen1. |
PMID | 11573155
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Topics |
- Adolescent
- Adult
- Burns, Chemical
(surgery)
- Child
- Eye Burns
(chemically induced, surgery)
- Female
- Follow-Up Studies
- Graft Rejection
(etiology, surgery)
- Humans
- Keratoplasty, Penetrating
- Male
- Middle Aged
- Postoperative Complications
(etiology, surgery)
- Reoperation
- Retrospective Studies
- Time Factors
- Treatment Outcome
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