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Molecular pathogenesis of the von Hippel-Lindau hereditary cancer syndrome: implications for oxygen sensing.

AuthorsH Yang, W G Kaelin Jr
JournalCell growth & differentiation : the molecular biology journal of the American Association for Cancer Research (Cell Growth Differ) Vol. 12 Issue 9 Pg. 447-55 (Sep 2001) ISSN: 1044-9523 [Print] United States
PMID11571227 (Publication Type: Journal Article, Review)
Chemical References
  • CUL2 protein, human
  • Cell Cycle Proteins
  • Cullin Proteins
  • Elongin
  • Transcription Factors
  • Tumor Suppressor Proteins
  • Ubiquitins
  • Ubiquitin-Protein Ligases
  • Von Hippel-Lindau Tumor Suppressor Protein
  • Ligases
  • VHL protein, human
  • Oxygen
Topics
  • Animals
  • Cell Cycle
  • Cell Cycle Proteins (metabolism)
  • Cullin Proteins
  • Disease Models, Animal
  • Elongin
  • Extracellular Matrix (metabolism)
  • Genotype
  • Humans
  • Hypoxia
  • Ligases (genetics, metabolism)
  • Neoplasms (physiopathology)
  • Oxygen (metabolism)
  • Phenotype
  • Protein Processing, Post-Translational
  • Transcription Factors (metabolism)
  • Tumor Suppressor Proteins
  • Ubiquitin-Protein Ligases
  • Ubiquitins (metabolism)
  • Von Hippel-Lindau Tumor Suppressor Protein
  • von Hippel-Lindau Disease (genetics, metabolism, physiopathology)

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