Accelerated atheroma, antiphospholipid antibodies, and the antiphospholipid syndrome.

Abstract	Indirect data coming from animal studies and in vitro observations support the contention that the mere presence of antiphospholipid antibodies may be sufficient to increase atheroma development, regardless of other predisposing factors. It seems that humoral and cellular immune responses to beta 2-glycoprotein I can play an important role in mediating the increased propensity to atherosclerosis.
Authors	J George, D Haratz, Y Shoenfeld
Journal	Rheumatic diseases clinics of North America (Rheum Dis Clin North Am) Vol. 27 Issue 3 Pg. 603-10, vii (Aug 2001) ISSN: 0889-857X [Print] United States
PMID	11534263 (Publication Type: Journal Article, Review)
Chemical References	Antibodies, Antiphospholipid Platelet Glycoprotein GPIb-IX Complex
Topics	Antibodies, Antiphospholipid (immunology) Antiphospholipid Syndrome (immunology, physiopathology) Arteriosclerosis (physiopathology) Humans Lupus Erythematosus, Systemic (complications) Platelet Glycoprotein GPIb-IX Complex (immunology)

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