Radiation therapy for Bowen's disease: lessons for lesions of the lower extremity.

Abstract

OBJECTIVE:

A retrospective outcomes review of radiotherapy for Bowen's disease was performed to analyze all patients treated with radiation therapy between 1993 and 1997 at the Naval Medical Center, San Diego.

METHODS:

Eleven patients with 16 lesions were treated with a median time-dose-fractionation value of 105 (range, 93-108).

RESULTS:

All 11 patients were without evidence of disease within 1 to 2 months of completing treatment. Four of the 16 lesions (25%) were unhealed at time of last follow-up; the remainder healed with good cosmetic result. All unhealed lesions were on the lower extremity. Median follow-up was 27.5 months (range, 9-57 months).

CONCLUSION:

Radiation remains a good therapeutic option in selected patients with Bowen's disease, but caution should be exercised before selection of patients with lesions in potentially poor healing areas, such as the lower extremity.

• Authors: M T Dupree, R A Kiteley, K Weismantle, R Panos, P A Johnstone
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 45 Issue 3 Pg. 401-4 (Sep 2001) ISSN: 0190-9622 [Print] United States
• PMID: 11511838 (Publication Type: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Review)

Topics

• Adult
• Aged
• Aged, 80 and over
• Bowen's Disease (pathology, radiotherapy)
• Female
• Humans
• Leg
• Male
• Medical Records
• Middle Aged
• Retrospective Studies
• Skin Neoplasms (pathology, radiotherapy)
• Treatment Outcome