[Effects of basic therapy of ischemic heart disease on vascular-platelet hemostasis during myocardial revascularization].

Abstract

Effects of preoperative therapy of coronary diseases with calcium antagonists and aspirin on vascular platelet hemostasis during aortocoronary shunting (ACS) have been studied in order to evaluate the role of hemostasis disorders in the pathogenesis of perioperative hemorrhagic complications. Therapy of coronary disease with these drugs during preparation to ACS can involve changes in platelet functional activity, depending on the individual sensitivity of patients. Drug-induced thrombocytopathy can induce pathological hemorrhages in the perioperative period of ACS.

• Authors: N A Vorob'eva, E V Nedashkovskiĭ
• Journal: Anesteziologiia i reanimatologiia (Anesteziol Reanimatol) 2001 May-Jun Issue 3 Pg. 47-50 ISSN: 0201-7563 [Print] Russia (Federation)
• Vernacular Title: Vliianie bazisnoĭ terapii IBS na sostoianie sosudisto-trombotsitarnogo gemostaza pri operatsii revaskuliarizatsii miokarda.
• PMID: 11510359 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Calcium Channel Blockers
• Fibrinolytic Agents
• Platelet Aggregation Inhibitors
• Aspirin

Topics

• Adult
• Aged
• Aspirin (pharmacology, therapeutic use)
• Blood Platelets (drug effects)
• Calcium Channel Blockers (pharmacology, therapeutic use)
• Coronary Artery Bypass
• Data Interpretation, Statistical
• Female
• Fibrinolytic Agents (pharmacology, therapeutic use)
• Hemostasis (drug effects)
• Humans
• Intraoperative Complications (etiology)
• Male
• Middle Aged
• Myocardial Ischemia (drug therapy, surgery)
• Platelet Aggregation Inhibitors (pharmacology, therapeutic use)
• Preoperative Care