[The evaluation of VNTR-polymorphism in the gene of dopamine transporter in men of different nationalities with acute alcoholic psychosis].

Abstract

VNTR-polymorphism of the gene of dopamine transporter (DAT) in men of the Russian and Tatar nationalities with acute alcoholic psychoses was analyzed by method of the polymerase chain reaction. There were no differences in the distribution of frequencies of genotypes and alleles of DAT gene between the populations examined. There was association between an allele variant with 9 units of DAT gene repetition (in homozygous state first of all), and early development of alcoholic dependence and acute alcoholic psychosis.

• Authors: A R Galeeva, E B Iur'ev, E K Khusnutdinova
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 101 Issue 5 Pg. 43-5 ( 2001) ISSN: 1997-7298 [Print] Russia (Federation)
• Vernacular Title: Otsenka VNTR-polimorfizma v gene perenoschika dofamina u muzhchin raznoĭ ĕtnicheskoĭ prinadlezhnosti s ostrym alkogol'nym psikhozom.
• PMID: 11505915 (Publication Type: English Abstract, Journal Article)

Chemical References

• Carrier Proteins
• Dopamine

Topics

• Acute Disease
• Adult
• Aged
• Biological Transport (physiology)
• Carrier Proteins (genetics, metabolism)
• Dopamine (genetics, metabolism)
• Gene Expression (genetics)
• Gene Frequency
• Humans
• Male
• Middle Aged
• Minisatellite Repeats (genetics)
• Psychoses, Alcoholic (ethnology, genetics)
• Russia (epidemiology)