Multiple adenomas and hepatocellular carcinoma in a renal transplant patient with glycogen storage disease type 1a (von Gierke disease).

Abstract

We report on a 42-year-old female patient with glycogen storage disease type 1a (von Gierke disease, GSD 1a) who developed hepatic adenomas and finally a hepatocellular carcinoma 10 years after renal transplantation. The tumor was resected; however, the patient died 6 months later as a result of fulminant carcinoma recurrence. In patients who have GSD 1a with terminal renal failure, combined liver and kidney transplantation may be considered at an early stage of the disease.

• Authors: J Gossmann, E H Scheuermann, A Frilling, H Geiger, C F Dietrich
• Journal: Transplantation (Transplantation) Vol. 72 Issue 2 Pg. 343-4 (Jul 27 2001) ISSN: 0041-1337 [Print] United States
• PMID: 11477366 (Publication Type: Case Reports, Journal Article)

Topics

• Adenoma (diagnosis, diagnostic imaging, surgery)
• Adult
• Carcinoma, Hepatocellular (diagnosis, diagnostic imaging, surgery)
• Fatal Outcome
• Female
• Glycogen Storage Disease Type I (complications)
• Humans
• Kidney Failure, Chronic (complications, surgery)
• Kidney Transplantation
• Liver Neoplasms (diagnosis, diagnostic imaging, surgery)
• Male
• Postoperative Complications
• Ultrasonography