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Efficacy of high dose steroid therapy in children with severe acute transverse myelitis.

Abstract
No effective treatment has been demonstrated for patients with acute transverse myelopathy. In a multicentre controlled study, 12 children with severe acute transverse myelopathy were treated with intravenous methylprednisolone (IVMP) and compared with a historical group of 17 patients. The treatment had a significant effect on the proportion of patients walking independently at 1 month and on the proportion with full recovery at 1 year, with no differences in the frequency of complications between the two groups.
AuthorsP Defresne, L Meyer, M Tardieu, E Scalais, C Nuttin, B De Bont, G Loftus, P Landrieu, H Kadhim, G Sébire
JournalJournal of neurology, neurosurgery, and psychiatry (J Neurol Neurosurg Psychiatry) Vol. 71 Issue 2 Pg. 272-4 (Aug 2001) ISSN: 0022-3050 [Print] England
PMID11459911 (Publication Type: Journal Article)
Chemical References
  • Methylprednisolone
Topics
  • Adolescent
  • Child
  • Child, Preschool
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Infant
  • Male
  • Methylprednisolone (administration & dosage, adverse effects)
  • Myelitis, Transverse (drug therapy)

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