[Detection of anti-HAV IgM and anti-HEV IgM in patients with sporadic acute hepatitis in Beijing between 1995-2000].

Abstract

OBJECTIVE:

To investigate the age ranges, liver function lesion and outcomes of sporadic acute hepatitis A and E in Beijing.

METHODS:

Enzyme immunoassay(EIA) was used for detection of anti-HAV and anti-HEV immunoglobulin M(IgM). Samples were collected from the patients with sporadic acute viral hepatitis in Beijing between 1995-2000.

RESULTS:

The total rate of positive for anti-HAV and anti-HEV was 55.2% (112) in 203 patients with acute hepatitis, 22.2% (45) and 33% (67) were positive separately for anti-HAV and anti-HEV in 112 patients. The duration of anti-HEV IgM was 45-60 days and that of anti-HAV IgM was at least 2-3 months. The patients with acute hepatitis A and hepatitis E all experienced jaundice, a rising of liver enzyme, but not developed to chronic hepatitis or to death.

CONCLUSION:

Acute hepatitis A as well as acute hepatitis E takes an important place in sporadic enterically transmitted hepatitis in Beijing.

• Authors: J Lu, H Zhao, Q Mong
• Journal: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology (Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi) Vol. 15 Issue 2 Pg. 157-9 (Jun 2001) ISSN: 1003-9279 [Print] China
• PMID: 11436647 (Publication Type: English Abstract, Journal Article)

Chemical References

• Hepatitis Antibodies
• Immunoglobulin M

Topics

• Acute Disease
• Adolescent
• Adult
• Child
• China (epidemiology)
• Hepatitis A (epidemiology, immunology)
• Hepatitis A virus (immunology)
• Hepatitis Antibodies (blood)
• Hepatitis E (epidemiology, immunology)
• Hepatitis E virus (immunology)
• Humans
• Immunoglobulin M (blood)
• Middle Aged