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The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts.

AbstractPURPOSE:
This study evaluated the use of enucleation and cryosurgery in the management of odontogenic keratocysts.
PATIENTS AND METHODS:
This study involved a retrospective review of 26 patients. All of the patients received a combination of enucleation and cryosurgery. Postoperative follow-up consisted of clinical and radiographic examinations.
RESULTS:
Before enucleation and cryotherapy, 22 of the 26 patients had received previous treatment consisting of enucleation alone. The average time from initial treatment to recurrence was 6.2 years. Twenty-three cases occurred in the mandible, 22 in the posterior (proximal to the canine), and 1 in the anterior mandible. Three cases involved the maxilla. Three of the 26 patients (11.5%) developed a recurrence after treatment. The average time from treatment to recurrence in these 3 patients was 1.6 years (range, 1.2 to 1.9 years). The remaining 23 patients (88.5%) had no evidence of clinical or radiographic recurrence. The average time of follow-up was 3.5 years (range, 2.0 to 10.0 years).
CONCLUSIONS:
Based on these results, the combination of enucleation and liquid nitrogen cryotherapy may offer patients improved therapy in the management of odontogenic keratocysts.
AuthorsB L Schmidt, M A Pogrel
JournalJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 59 Issue 7 Pg. 720-5; discussion 726-7 (Jul 2001) ISSN: 0278-2391 [Print] United States
PMID11429726 (Publication Type: Evaluation Study, Journal Article)
CopyrightCopyright 2001 American Association of Oral and Maxillofacial Surgeons
Chemical References
  • Nitrogen
Topics
  • Adolescent
  • Adult
  • Aged
  • Bone Transplantation
  • Child
  • Cryosurgery
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mandibular Diseases (diagnostic imaging, surgery)
  • Maxillary Diseases (diagnostic imaging, surgery)
  • Middle Aged
  • Nitrogen (therapeutic use)
  • Odontogenic Cysts (diagnostic imaging, surgery)
  • Osteotomy
  • Radiography
  • Recurrence
  • Retrospective Studies
  • Time Factors
  • Wound Healing

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