[Efficacy of modified ultrafiltration in coronary artery bypass grafting].

Abstract

We evaluated the efficacy of modified ultrafiltration (MUF) in coronary artery bypass grafting. Twenty patients were divide into two groups consisting of a control group (n = 11) and a MUF group (n = 9). MUF was carried out for fifteen minutes immediately after the completion of cardiopulmonary bypass. The blood flow through the ultrafilter was 300 ml/min and about 1,200 ml of water was removed. The hematocrit elevated significantly from 25% to 30% in the MUF group (p < 0.01). Postoperative blood loss in the first 24 hours in the MUF group was significantly less than that in the control group (8 +/- 2 ml/kg vs 12 +/- 4 ml/kg, p < 0.01). There was no statistical difference in the percentage of the increase in body weight after the operation, inflammatory reaction and pulmonary function (A-a DO2, PaO2/FIO2 and duration of intubation) between two groups. In conclusion, MUF is useful to hemoconcentrate and reduce postoperative blood loss in coronary artery bypass grafting.

• Authors: M Kamada, K Niibori, H Akimoto, H Yokoyama, M Tofukuji, A Iguchi, M Ohmi, K Tabayashi, S Kikuchi, T Matsuura
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 54 Issue 6 Pg. 463-7 (Jun 2001) ISSN: 0021-5252 [Print] Japan
• PMID: 11424495 (Publication Type: English Abstract, Journal Article)

Topics

• Aged
• Aortic Aneurysm, Thoracic (surgery)
• Coronary Artery Bypass
• Female
• Heart Valve Diseases (surgery)
• Hematocrit
• Hemofiltration (methods)
• Humans
• Male
• Middle Aged
• Reoperation