[LDL-apheresis: current status].

Abstract

PURPOSE:

State of the art of LDL-apheresis and treatment of severe familiar hypercholesterolemia.

PATIENTS AND METHODS:

Clinical experience of treatment with LDL-apheresis of pediatric and adult patients with familial hypercholesterolemia using the following techniques: D.A.L.I., H.E.L.P., D.S.C.

RESULTS:

The outcome of treatment with LDL-apheresis in young patients, using the most recently introduced techniques, is reported. We have submitted to LDL-apheresis 11 pediatric patients. The youngest is aged 3.5. LDL-apheresis is able at improving the metabolic impairment and halting the natural evolution of atherosclerotic disease and atherosclerotic complications.

CONCLUSIONS:

At present, LDL-apheresis is the most effective and safe therapeutic approach to the treatment of homozygous, heterozygous and double heterozygous familial hypercholesterolemia.

• Authors: C Stefanutti, A Vivenzio, G Lucani, S Di Giacomo
• Journal: La Clinica terapeutica (Clin Ter) 2001 Jan-Feb Vol. 152 Issue 1 Pg. 65-9 ISSN: 0009-9074 [Print] Italy
• Vernacular Title: La LDL-Aferesi: stato attuale.
• PMID: 11382172 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Lipoproteins, LDL

Topics

• Blood Component Removal
• Humans
• Hyperlipoproteinemia Type II (therapy)
• Lipoproteins, LDL