Failed treatment of abdominal pregnancy with methotrexate. A case report.

Abstract

BACKGROUND:

Methotrexate is an effective, safe, low-cost alternative to surgery for treating tubal pregnancies. To our knowledge, there have only been two other reported attempts at treating abdominal pregnancy with methotrexate.

CASE:

Despite two courses of treatment with methotrexate, the pregnancy persisted, and laparoscopy permitted a tissue diagnosis of abdominal pregnancy.

CONCLUSION:

Although treatment with methotrexate was not successful in this case, its potential use in abdominal pregnancies merits further investigation.

• Authors: M Zinger, D Rosenfeld
• Journal: The Journal of reproductive medicine (J Reprod Med) Vol. 46 Issue 4 Pg. 392-4 (Apr 2001) ISSN: 0024-7758 [Print] United States
• PMID: 11354843 (Publication Type: Case Reports, Journal Article)

Chemical References

• Abortifacient Agents, Nonsteroidal
• Methotrexate

Topics

• Abortifacient Agents, Nonsteroidal (administration & dosage, therapeutic use)
• Adult
• Female
• Humans
• Infertility, Female
• Injections, Intramuscular
• Methotrexate (administration & dosage, therapeutic use)
• Pregnancy
• Pregnancy, Abdominal (drug therapy, surgery)
• Treatment Failure