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The prognostic value of human placental lactogen (HPL) levels in threatened abortion.

Abstract
The value of a single HPL estimation in serum was assessed in 337 patients with a threatened abortion between 7 and 27 weeks gestation. Serial assays were subsequently performed on 75 of these. A scheme is proposed whereby an HPL result can be given a "favourable", "equivocal" or "unfavourable" prognosis according to its level. Using this scheme a correct prognosis was obtained in 86 per cent of cases between 9 and 19 weeks gestation while an incorrect prognosis was obtained in 3 per cent of cases. There appeared to be little prognostic value after 19 weeks gestation though prior to 9 weeks the results were sufficiently promising to suggest that a more sensitive assay would be useful.
AuthorsM W Gartside, V R Tindall
JournalBritish journal of obstetrics and gynaecology (Br J Obstet Gynaecol) Vol. 82 Issue 4 Pg. 303-9 (Apr 1975) ISSN: 0306-5456 [Print] England
PMID1125152 (Publication Type: Journal Article)
Chemical References
  • Placental Lactogen
Topics
  • Abortion, Induced
  • Abortion, Threatened (blood, diagnosis)
  • Female
  • Hospitalization
  • Humans
  • Length of Stay
  • Placental Lactogen (blood)
  • Pregnancy
  • Prognosis
  • Time Factors

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