Abstract |
Diffuse mesangial sclerosis is a rare renal disease, occurring either in isolation or as part of Denys-Drash syndrome. Denys-Drash syndrome originates from mutations of the Wilms tumor suppressor gene (WT1 ). We describe the presence of WT1 mutations in 7 Japanese children with isolated diffuse mesangial sclerosis.
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Authors | S Ito, A Takata, H Hataya, M Ikeda, H Kikuchi, J Hata, M Honda |
Journal | The Journal of pediatrics
(J Pediatr)
Vol. 138
Issue 3
Pg. 425-7
(Mar 2001)
ISSN: 0022-3476 [Print] United States |
PMID | 11241056
(Publication Type: Journal Article)
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Topics |
- Female
- Genes, Wilms Tumor
(genetics)
- Glomerular Mesangium
(pathology)
- Humans
- Infant
- Infant, Newborn
- Japan
- Kidney Diseases
(genetics, surgery)
- Kidney Transplantation
- Male
- Point Mutation
- Sclerosis
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