Abstract | OBJECTIVE: RESEARCH METHODS AND PROCEDURES: We measured serum IL-6 levels in 25 obese patients (body mass index of >35 kg/m2) and 12 healthy women. RESULTS: The results demonstrate statistically significant differences in serum IL-6 levels between the control group (1.28 +/- 0.85 pg/mL) and obese patients without OSAS (7.69 +/- 5.06 pg/mL, p < 0.05) and with OSAS (5.58 +/- 0.37 pg/mL, p < 0.0005). In the patients with OHS, IL-6 concentrations were highest (43.13 +/- 24.27 pg/mL). DISCUSSION: We conclude that serum IL-6 is increased in obese patients. The highest IL-6 levels were found in the patients with OHS.
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Authors | L Roytblat, M Rachinsky, A Fisher, L Greemberg, Y Shapira, A Douvdevani, S Gelman |
Journal | Obesity research
(Obes Res)
Vol. 8
Issue 9
Pg. 673-5
(Dec 2000)
ISSN: 1071-7323 [Print] United States |
PMID | 11225716
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
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Chemical References |
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Topics |
- Adult
- Female
- Humans
- Hypoventilation
(blood, complications)
- Interleukin-6
(blood)
- Male
- Middle Aged
- Obesity
(blood, complications, physiopathology)
- Oxygen Consumption
(physiology)
- Sleep Apnea, Obstructive
(blood, complications)
- Syndrome
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