Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children.

Abstract

In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.

• Authors: R M Kline, J J Kline, Di Palma J, G J Barbero
• Journal: The Journal of pediatrics (J Pediatr) Vol. 138 Issue 1 Pg. 125-8 (Jan 2001) ISSN: 0022-3476 [Print] United States
• PMID: 11148527 (Publication Type: Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Parasympatholytics
• Plant Oils
• Tablets, Enteric-Coated
• peppermint oil

Topics

• Abdominal Pain (diagnosis, etiology)
• Adolescent
• Age Factors
• Child
• Colonic Diseases, Functional (complications, drug therapy, physiopathology)
• Double-Blind Method
• Female
• Humans
• Hydrogen-Ion Concentration
• Male
• Mentha piperita
• Pain Measurement
• Parasympatholytics (therapeutic use)
• Plant Oils (therapeutic use)
• Severity of Illness Index
• Tablets, Enteric-Coated (therapeutic use)
• Treatment Outcome