HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Critical care of HELLP syndrome with corticosteroids.

Abstract
HELLP syndrome is a special type of severe preeclampsia that constitutes a management dilemma for obstetricians. The high maternal and perinatal morbidity (and rarely maternal mortality) that can result from this entity mandates continuing efforts to find an effective treatment or prevention. The traditional therapy for HELLP syndrome has been meticulous medical care of the mother, vigilant fetal surveillance, and timely delivery. Proposed new therapies to permit prolongation of preterm pregnancy and fetal maturation include vasodilation therapy using fluids and antihypertensives and intensive corticosteroid therapy using intravenously administered high dose dexamethasone, usually in a dose of 10 mg every 12 hours. The latter therapy appears to improve fetal and maternal health with the added benefit of accelerating postpartum recovery from HELLP syndrome.
AuthorsE F Magann, J N Martin Jr
JournalAmerican journal of perinatology (Am J Perinatol) Vol. 17 Issue 8 Pg. 417-22 ( 2000) ISSN: 0735-1631 [Print] United States
PMID11142392 (Publication Type: Journal Article, Review)
Chemical References
  • Anti-Inflammatory Agents
  • Dexamethasone
Topics
  • Anti-Inflammatory Agents (administration & dosage)
  • Critical Care
  • Dexamethasone (administration & dosage)
  • Female
  • HELLP Syndrome (prevention & control)
  • Humans
  • Infusions, Intravenous
  • Obstetric Labor, Premature (prevention & control)
  • Pregnancy

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: