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Highly specific inhibitory effect of three-component hybrid liposomes including sugar surfactants on the growth of glioma cells.

Abstract
Three-component hybrid liposomes composed of L-alpha-dimyristoylphosphatidylcholine, micellar surfactant (Tween 20), and beta-D-fructofuranosyl-alpha-D-glucopyranoside monododecanoate were found to be highly effective for inhibiting the growth of glioma cells without any drug.
AuthorsY Matsumoto, T Kato, H Suzuki, S Hirose, Y Naiki, M Hirashima, R Ueoka
JournalBioorganic & medicinal chemistry letters (Bioorg Med Chem Lett) Vol. 10 Issue 23 Pg. 2617-9 (Dec 04 2000) ISSN: 0960-894X [Print] England
PMID11128636 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Carbohydrates
  • Liposomes
  • Surface-Active Agents
Topics
  • Carbohydrates (chemistry)
  • Cell Division (drug effects)
  • Drug Screening Assays, Antitumor
  • Glioma (pathology)
  • Humans
  • Liposomes
  • Membrane Fluidity
  • Molecular Structure
  • Surface-Active Agents (chemistry, pharmacology)
  • Tumor Cells, Cultured

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