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[1: Clinical aspects, laboratory diagnosis and therapy. Low backache--when is sacroiliitis the cause?].

Abstract
Despite the availability of modern imaging modalities, early diagnosis of sacroiliitis remains a challenge. The patient's history and the results of the clinical examination form the basis for establishing a working diagnosis, which then needs to be confirmed by laboratory tests and diagnostic imaging. Common causes of sacroiliitis are inflammatory diseases of the spine, in particular seronegative spondyloarthropathies; infectious sacroiliitis is much less common. Besides serological testing (HLA-B27), imaging techniques are essential for diagnosing early forms of sacroiliitis. The treatment of the condition initially involves the use of non-steroidal anti-inflammatory drugs (NSAIDs). In patients with infectious sacroiliitis, antibiotics are the treatment of choice. Local application of steroids, or physiotherapy, can be helpful. The value of disease-modifying drugs (DMARDs) (sulfasalazine, methotrexate) has not been verified, and is questionable. New approaches such as anti-tumor necrosis factor alpha (anti-TNF alpha) need to be tested in controlled studies.
AuthorsH Kellner, W Kellner
JournalMMW Fortschritte der Medizin (MMW Fortschr Med) Vol. 142 Issue 41 Pg. 30-4 (Oct 12 2000) ISSN: 1438-3276 [Print] Germany
Vernacular TitleTeil 1: Klinik, Labordiagnostik und Therapie. Kreuzschmerzen--Wann steckt eine Sakroiliitis dahinter?
PMID11085073 (Publication Type: English Abstract, Journal Article)
Topics
  • Arthritis (diagnosis, etiology, therapy)
  • Back Pain (etiology, therapy)
  • Diagnosis, Differential
  • Humans
  • Sacroiliac Joint

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