Viability of Q-wave infarcted myocardium with restored positive and persistent negative T waves after optimal revascularization compared with dobutamine stress echocardiography.

Abstract

To clarify the clinical difference in viability of myocardium with negative and positive T waves in Q-wave anterior or anteroseptal myocardial infarction, we performed low-dose dobutamine stress echocardiography in 17 patients with negative T waves and in 13 patients with positive T waves with optimal revascularization of infarct-related arteries in the chronic phase of infarction. At baseline the wall motion score (WMS) of the negative and positive T groups was 25.8 +/- 3.0 and 22.3 +/- 2.2 points (p <0.05), respectively. At peak stress WMS in each group was 27.2 +/- 4.2 and 19.8 +/- 2.4 points (p <0.0001), respectively. With dobutamine stress WMS in the positive T group was more decreased than that of the negative T group (p <0.0001). We conclude that the restored positive T waves in Q-wave myocardial infarction indicate a significantly greater amount of viable myocardium than the negative T waves, showing better regional wall motion improvement with low-dose dobutamine stress.

• Authors: S Watanabe, Y Kawamura, Y Watanabe, K Tanaka, K Tanaka, Y Takei, N Ejiri, K Shimada
• Journal: The American journal of cardiology (Am J Cardiol) Vol. 85 Issue 1 Pg. 31-6 (Jan 01 2000) ISSN: 0002-9149 [Print] United States
• PMID: 11078232 (Publication Type: Comparative Study, Journal Article, Validation Study)

Chemical References

• Cardiotonic Agents
• Dobutamine
• Creatine Kinase

Topics

• Aged
• Cardiotonic Agents
• Coronary Angiography
• Creatine Kinase (blood)
• Dobutamine
• Echocardiography (methods)
• Electrocardiography (methods)
• Exercise Test (methods)
• Female
• Follow-Up Studies
• Hemodynamics
• Humans
• Male
• Middle Aged
• Myocardial Infarction (diagnosis, enzymology, physiopathology, therapy)
• Myocardial Revascularization (methods)
• Prognosis
• Sensitivity and Specificity
• Severity of Illness Index